American Head & Neck Society

Advancing Education, Research, and Quality of Care for the Head and Neck oncology patient.

Published on by Farhoud Faraji

Farhoud Faraji – San Diego, California

Practice Contact Information

UC San Diego Health
200 West Arbor Drive
MC8895
San Diego
California
92103
United States

Phone: 9165089300
Email: f1faraji@health.ucsd.edu
Web Site: https://medschool.ucsd.edu/som/surgery/divisions/Otolaryngology/education/residency/Pages/current-residents.aspx

Areas of surgical specialization in Head and Neck Surgery

Endocrine Surgery, Head and Neck Research, Head and Neck Surgeon, Reconstructive Head & Neck Surgery

Biography/Statement

I am an Otolaryngology Head and Neck surgery resident trainee in the NIH T32 surgeon scientist pathway at UC San Diego Health. My aim is to train as a head and neck surgical oncologist and surgeon scientist. My research interests include the genomics, genetics, molecular biology, and mouse modeling of head and neck malignancies.

Clinical Trials

Bibliography

Primary Literature:

  • Lee JH, Mohamed T, Ramsey C, Kim J, Kane S, Gold K, Faraji F, Califano JA. A Hospital-wide Intervention to Improve Compliance with TNM Cancer Staging Documentation Running head: Improving TNM Cancer Staging Compliance. In press at JNCCN.
  • Gerkin RC, Ohla K, Veldhuizen MG, Joseph PV, Kelly CE, Bakke AJ, Steele KE, Farruggia MC, Pellegrino R, Pepino MY, Bouysset C, Soler GM, Pereda-Loth V, Dibattista M, Cooper KW, Croijmans I, Di Pizio A, Ozdener MH, Fjaeldstad AW, Lin C, Sandell MA, Singh PB, Brindha VE, Olsson SB, Saraiva LR, Ahuja G, Alwashahi MK, Bhutani S, D’Errico A, Fornazieri MA, Golebiowski J, Hwang LD, Öztürk L, Roura E, Spinelli S, Whitcroft KL, Faraji F, Fischmeister FPS, Heinbockel T, Hsieh JW, Huart C, Konstantinidis I, Menini A, Morini G, Olofsson JK, Philpott CM, Pierron D, Shields VDC, Voznessenskaya VV, Albayay J, Altundag A, Bensafi M, Bock MA, Calcinoni O, Fredborg W, Laudamiel C, Lim J, Lundström JN, Macchi A, Meyer P, Moein ST, Santamaría E, Sengupta D, Domínguez PP, Yanık H, Boesveldt S, de Groot JHB, Dinnella C, Freiherr J, Laktionova T, Mariño S, Monteleone E, Nunez-Parra A, Abdulrahman O, Ritchie M, Thomas-Danguin T, Walsh-Messinger J, Al Abri R, Alizadeh R, Bignon E, Cantone E, Cecchini MP, Chen J, Guàrdia MD, Hoover KC, Karni N, Navarro M, Nolden AA, Mazal PP, Rowan NR, Sarabi-Jamab A, Archer NS, Chen B, Di Valerio EA, Feeney EL, Frasnelli J, Hannum M, Hopkins C, Klein H, Mignot C, Mucignat C, Ning Y, Ozturk EE, Peng M, Saatci O, Sell EA, Yan CH, Alfaro R, Cecchetto C, Coureaud G, Herriman RD, Justice JM, Kaushik PK, Koyama S, Overdevest JB, Pirastu N, Ramirez VA, Roberts SC, Smith BC, Cao H, Wang H, Balungwe P, Baguma M, Hummel T, Hayes JE, Reed DR, Niv MY, Munger SD, Parma V. The best COVID-19 predictor is recent smell loss: a cross-sectional study. 2020. doi: 10.1101/2020.07.22.20157263. In press at Chemical Senses.
  • Jumaily M, Gallogly JA, Gropler MC, Faraji F, Ward GM. Does subglottic squamous cell carcinoma warrant a different strategy than other laryngeal subsites? 2020 Aug 26. doi: 10.1002/lary.28946.
  • Klebaner D, Saddawi-Konefka R, Finegersh A, Yan CH, Califano JA, London NR, Deconde AS†, Faraji F†. Immunotherapy in sinonasal melanoma: treatment patterns and outcomes relative to cutaneous melanoma. Int Forum Allergy Rhinol. 2020 Jul 5. doi: 10.1002/alr.22628.
  • Parma V, Ohla K, Veldhuizen MG, Niv MY, Kelly CE, Bakke AJ, Cooper KW, Bouysset C, Pirastu N, Dibattista M, Kaur R, Liuzza MT, Pepino MY, Schöpf V, Pereda-Loth V, Olsson SB, Gerkin RC, Rohlfs Domínguez P, Albayay J, Farruggia MC, Bhutani S, Fjaeldstad AW, Kumar R, Menini A, Bensafi M, Sandell M, Konstantinidis I, Di Pizio A, Genovese F, Öztürk L, Thomas-Danguin T, Frasnelli J, Boesveldt S, Saatci Ö, Saraiva LR, Lin C, Golebiowski J, Dar Hwang L, Ozdener MH, Guàrdia MD, Laudamiel C, Ritchie M, Havlícek J, Pierron D, Roura E, Navarro M, Nolden AA, Lim J, Whitcroft KL, Colquitt LR, Ferdenzi C, Brindha EV, Altundag A, Macchi A, Nunez-Parra A, Patel ZM, Fiorucci S, Philpott CM, Smith BC, Lundström JN, Mucignat C, Parker JK, van den Brink M, Schmuker M, Fischmeister FPS, Heinbockel T, Shields VDC, Faraji F, Santamaría E, Fredborg WEA, Morini G, Olofsson JK, Jalessi M, Karni N, D’Errico A, Alizadeh R, Pellegrino R, Meyer P, Huart C, Chen B, Soler GM, Alwashahi MK, Welge-Lüssen A, Freiherr J, de Groot JHB, Klein H, Okamoto M, Singh PB, Hsieh JW, Reed DR, Hummel T, Munger SD, Hayes JE; GCCR Group Authors. More than smell – COVID-19 is associated with severe impairment of smell, taste, and chemesthesis. Chem Senses. 2020 Jun 20:bjaa041. doi: 10.1093/chemse/bjaa041.
  • Jaime-Lara R, Parma V, Yan C, Faraji F, Joseph P. The Role of Olfaction in Human Health: A Focus on Coronaviruses. Allergy Rhinol (Providence). 2020 Jun 5;11:2152656720928245. doi: 10.1177/2152656720928245.
  • Finegersh A, Moss W, Saddawi-Konefka R, Faraji F, Coffey C, Califano J, Brumund K, Orosco R. A meta-analysis of risk of occult lymph node metastasis in the irradiated, clinically N0 neck. Head & Neck. 2020 May 19. doi: 10.1002/hed.26248.
  • Yan CH, Faraji F, Prajapati DP, Ostrander BT, DeConde AS. Self-reported olfactory loss associates with outpatient clinical course in Covid-19. Int Forum Allergy Rhinol. 2020 April 24. doi: 10.1002/alr.22592.
  • Faraji F*, Lee JH*, Faraji F, MacDonald B, Oviedo P, Stuart E, Baxter M, Lance SH, Gosman AA, Castillo EM, Hom DB. Electric Scooter Craniofacial Trauma. Laryngoscope Investigational Otolaryngology. 2020 Apr 7;5(3):390-395. doi: 10.1002/lio2.380.
  • Pang J, Crawford K, Faraji F, Ramsey C, Kemp A, Orosco RK, Califano JA. An analysis of 1-year charges for head and neck cancer: targets for value-based interventions. Otolaryngology-Head and Neck Surgery. 2020 May 26. doi: 10.1177/0194599820921401.
  • Yan CH, Faraji F, Prajapati DP, Boone CE, DeConde AS. Association of chemosensory dysfunction and Covid-19 presenting with influenza-like symptoms. Int Forum Allergy Rhinol. 2020 Apr 12. doi: 10.1002/alr.22579.
  • Devries J, Faraji F, Bracken D, Weissbrod PA. An Atypical Cause of Difficulty Swallowing. JAMA Otolaryngol Head Neck Surg. JAMA Otolaryngol Head Neck Surg. 2020 Mar 19. doi: 10.1001/jamaoto.2020.0133.
  • Faraji F, Aygun N, Coquia SF, Gourin CG, Eisele DW, Fakhry C. Computed tomography performance in predicting extranodal extension in HPV-positive oropharynx cancer. 2019 Aug 14. doi: 10.1002/lary.28237.
  • Jumaily M, Faraji F, Walker RJ, Osazuwa-Peters N, Ward GW. Prognostic significance of surgical margins after transoral laser microsurgery for T1 and T2 glottic carcinoma. Oral Oncol. 2019 Oct; 97:105-111.
  • Windon MJ, D’Souza G, Faraji F, Gourin CG, Kiess A, Koch W, Eisele DW, Fakhry C. Priorities of human papillomavirus-associated oropharyngeal cancer patients at diagnosis and after treatment. Oral Oncol. 2019 Aug;95:11-15.
  • Faraji F, Fung N, Zaidi M, Gourin CG, Eisele DW, Rooper LM, Fakhry C. Tumor infiltrating lymphocyte quantification stratifies early stage HPV oropharynx cancer prognosis. 2019 May 9.
  • Moss W, Faraji F, Jafari A, DeConde A. A systematic review of the nasal septal turbinate: an overlooked surgical target. Am J Otolaryngol. 2019 Nov – Dec;40(6):102188.
  • Faraji F, Crawford K, Stramiello J, Jafari A, Weissbrod PA, Brumund KT. Bullous pemphigoid presenting as oropharyngeal hemorrhage. JAMA Otolaryngol Head Neck Surg. 2019 Jan 24.
  • Windon MJ, D’Souza G, Faraji F, Gourin CG, Kiess A, Koch W, Eisele DW, Fakhry C. Priorities, concerns, and regret among head and neck cancer patients. 2019 Apr 15;125(8):1281-1289.
  • Jumaily M, Faraji F, Walker RJ, Ward GM. Basaloid Squamous Cell Carcinoma of the Larynx: A National Cancer Database Analysis. Otolaryngol Head Neck Surg. 2019 May;160(5):847-854.
  • Faraji F, Rettig EM, El Asmar M, Fung N, Eisele DW, Fakhry C. The prevalence of HPV in oropharyngeal cancer is increasing regardless of sex or race, and the influence of sex and race on survival is modified by HPV tumor status. In press at Cancer.
  • Gallogly J, Jumaily M, Faraji F, Mikulec AA. Stereotactic radiotherapy in three weekly fractions for the management of vestibular schwannomas. Am J Otolaryngol. 2018 Jun 22. pii: S0196-0709(18)30514-3.
  • Rettig EM, Zaidi M, Faraji F, Eisele DW, El Asmar M, D’Souza G, Fakhry C. Increasing Age of HPV-Positive and HPV-Negative Oropharyngeal Cancer Patients Over Time: Analysis of the National Cancer Database. Under revision at Oral Oncology. Oral Oncology. 2018 Aug; 83:147-153.
  • Ward Y, Lake R, Faraji F, Sperger J, Martin P, Gilliard C, Ku KP, Rodems T, Niles D, Tillman H, Yin J, Hunter K, Sowalsky A, Lang J, Kelly K. CD97 on Tumor Cells Binds Platelets and Mediates Bidirectional Signaling to Promote Transendothelial Migration and Metastasis. 2018 April; 23(3): 808–822.
  • Gallogly J, Faraji F, Jumaily M, Brunworth JD. Diagnostic dilemmas of mechanical restriction of the medial rectus: a case report. Allergy Rhinol (Providence). 2018 April; 8(1): e40-44.
  • Faraji F, Coquia SF, Wenderoth MB, Padilla ES, Blitz D, DeJong MR, Aygun N, Hamper U, Fakhry C. Evaluating oropharyngeal carcinoma with transcervical ultrasonography, CT, and MRI. Oral Oncology. 2018 Mar; 78:177-185.
  • Faraji F, Padilla ES, Blitz D, Wenderoth MB, Blanco RG, Kawamoto S, Hamper U, Fakhry C. Reader performance in the ultrasonographic evaluation of oropharyngeal carcinoma. Oral Oncology. 2018 Feb; 77:105-110.
  • Guntupalli L, Patel K, Faraji F, Brunworth JD. Perforation of the nasal septum and positive antinuclear antibody titers: which autoimmune disorders are most often associated with nasal septum perforation? Allergy Rhinol (Providence). 2017 Mar 1; 8(1):40-44.
  • Jumaily M, Faraji F, Mikulec AA. Intratympanic triamcinolone and dexamethasone in the treatment of Meniere’s syndrome. Otol Neurotol. 2017 Mar;38(3):386-391.
  • Patel K, Faraji F, Brunworth JD. Isolated craniopharyngioma in the nasal cavity. Acta Otolaryngol Case Reports. 2016 Jan; 1(1):98-101.
  • Jumaily M, Faraji F, Brunworth JD. Endoscopic orbital exenteration in the treatment of acute invasive fungal sinusitis. Acta Otolaryngol Case Reports. 2016 Jan; 1(1):58-62.
  • Faraji F, Antisdel JL, Brunworth JD. Blindness Resulting from Bisphosphonate-Related Osteonecrosis of the Skull Base. Acta Otolaryngol Case Reports. 2016 Jan; 1(1):49-53.
  • Bai L, Yang H, Hu Y, Shukla A, Ha NH, Doran A, Faraji F, Goldberger NE, Lee M, Keane T, Hunter KW. An integrated genome-wide systems genetics screen for breast cancer metastasis susceptibility genes. PLoS Genet. 2016 Apr 13; 12(4): e1005989.
  • Faraji F, Hu Y, Yang HH, Lee MP, Winkler GS, Hafner M, Hunter KW. Post-transcriptional control of tumor cell autonomous metastatic potential by CCR4-NOT deadenylase Cnot7. PLoS Genet. 2016 Jan 25; 12(1): e1005820.
  • Geiger TR, Ha NH, Faraji F, Michael HT, Rodriguez L, Walker RC, Green JE, Simpson RM, Hunter KW. Functional analysis of prognostic gene expression network genes in metastatic breast cancer models. PLoS One. 2014 Nov 4; 9(11): e111813.
  • Faraji F, Hu Y, Wu G, Goldberger NE, Walker R, Zhang J, Hunter KW. An Integrated Systems Genetics Screen Reveals the Transcriptional Structure of Predisposition to Metastatic Disease. Genome Res. 2014 Feb; 24(2):227-40.
  • Alsarraj J, Faraji F, Geiger TR, Mattaini KR, Williams M, Wu J, Ha NH, Merlino T, Walker RC, Bosley A, Xiao Z, Andresson T, Esposito D, Smithers N, Lugo D, Prinjha R, Day A, Crawford NP, Ozato K, Gardner K, Hunter KW. BRD4 Short Isoform Interacts with RRP1B, SIPA1 and Components of the LINC Complex at the Inner Face of the Nuclear Membrane. PLoS ONE. 2013 Nov 19; 8(11): e80746.
  • Faraji F, Pang Y, Walker R, Nieves Borges R, Yang L, Hunter KW. Cadm1 Is a Metastasis Susceptibility Genet That Suppresses Metastasis by Modifying Tumor Interaction with the Cell-Mediated Immunity. PLoS Genet. 2012 Sept; 8(9): e1002926.
    • PLoS Genetics cover illustration for the September 2012 issue by Faraji F & Geiger TR.
    • Highlighted with a Perspective article in PLoS Genetics: Drinkwater NR, Gould MN (2012) The Long Path from QTL to Gene. PLoS Genet 8(9): e1002975.
    • Featured in the November issue of the NIH Graduate Student Chronicles.
  • Mikulec AA, Faraji F, Kinsella LJ. Evaluation of the Efficacy of Caffeine Cessation, Nortriptyline, and Topiramate in the Treatment of Vestibular Migraine and Complex Dizziness of Unknown Etiology. Am J Otolaryngol. 2012 Jan-Feb; 33(1):121-7.
  • Young JJ, Cherone JM, Doyon Y, Ankoudinova I, Faraji F, Lee AH, Ngo C, Guschin DY, Paschon DE, Miller JC, Zhang L, Rebar EJ, Gregory PD, Urnov FD, Harland RM, Zeitler B. Efficient targeted gene disruption in the soma and germ line of the frog Xenopus tropicalis using engineered zinc-finger nucleases. PNAS. 2011 Apr 26; 108(17):7052-7.
  • Faraji F, Kinsella LJ, Rutlege JC, Mikulec AA. The Comparative Usefulness of Orthostatic Testing and Tilt Table Testing in the Evaluation of Autonomic-Associated Dizziness. Otol Neurotol. 2011 Jun; 32(4):654-9.
  • Cai CQ, Doyon Y, Ainley WM, Miller JC, Dekelver RC, Moehle EA, Rock JM, Lee YL, Garrison R, Schulenberg L, Blue R, Worden A, Baker L, Faraji F, Zhang L, Holmes MC, Rebar EJ, Collingwood TN, Rubin-Wilson B, Gregory PD, Urnov FD, Petolino JF. Targeted transgene integration in plant cells using designed zinc finger nucleases. Plant Mol Biol. 2009 Apr; 69(6):699-709.
  • Doyon Y, McCammon JM, Miller JC, Faraji F, Ngo C, Katibah GE, Amora R, Hocking TD, Zhang L, Rebar EJ, Gregory PD, Urnov FD, Amacher SL. Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases. Nat Biotechnol. 2008 Jun; 26(6):702-8.

* equal contribution

† co-corresponding authors

 

Review Articles:

  • Fung N*, Faraji F*, Kang H, Fakhry C. The role of human papillomavirus on the prognosis and treatment of oropharyngeal carcinoma. Cancer Metastasis Reviews. 2017 Sep; 36(3):449-461.
  • Faraji F*, Zaidi M*, Fakhry C, Gaykalova DA. Molecular mechanisms of human papillomavirus-related carcinogenesis in head and neck cancer. Microbes Infect. 2017 Sep-Oct; 19(9-10):464-475.
  • Faraji F, Eisele DW, Fakhry C. Emerging insights into recurrent and metastatic human papillomavirus-related oropharyngeal squamous cell carcinoma. Laryngoscope Investig Otolaryngol. 2017 Jan 17.
  • Faraji F, Eissenberg JC. Seed and Soil: A Conceptual Framework of Metastasis for Clinicians. Mo Med. 2013 Jul-Aug;110(94):302-8.

*equal contribution

 

Book Chapters:

  • Faraji F, Fakhry C. Chapter 13 – Oropharyngeal HPV and head and neck cancer. In Bosch FX, Jenkins D (eds). Human Papillomavirus: Proving and Using a Viral Cause for Cancer. Academic Press: Cambridge, MA, 2020.
  • Faraji F, Schubert AD, Kagohara LT, Tan M, Xu Y, Zaidi M, Fortin JP, Fakhry C, Izumchenko E, Gaykalova D, Fertig EJ. Chapter 15 – The Genome-wide molecular landscape of HPV-driven and HPV-negative head and neck squamous cell carcinoma. In Burtness B, Golemis EA (eds) Molecular Determinants of Head and Neck Cancer. 2nd Humana Press: New York, NY, 2018.
  • Faraji F, Fakhry C. Chapter 4 – HPV-related Head and Neck Cancer Biology. In Argiris A, Rosenthal DI, Ferris RL (eds) Head and Neck Cancers: Evidence-based Treatment. Demos Medical: New York, NY, 2018.
  • Faraji F, Fakhry C. Chapter 28 – Human papillomavirus and head and neck cancer. In Durand M, Deschler D (eds) Infections of the Ears, Nose, Throat, and Sinuses. Springer: New York, 2018.
  • Ha, NH, Faraji F, Hunter KW. Chapter 17 – Mechanisms of Metastasis. In Bae YH, Mrsny RJ, Park K (eds) Cancer Targeted Drug Delivery: An Elusive Dream. Springer: New York, NY, 2013.

 

Published Abstracts:

  • Corredor G, Lewis J, Lu C, Toro P, Fu P, Thorstad W, Bishop W, Bishop J, Faraji F, Madabhushi A. The Spatial Patterns of Tumor-Infiltrating Lymphocytes (TILs) are More Prognostic Than TIL Density in p16+ Oropharyngeal Squamous Cell Carcinoma Patients. Lab Invest. 2020; 100 (SUPPL 1), 1187-1188.
  • Faraji F, Brunworth JD. Blindness Resulting from Bisphosphonate-Related Osteonecrosis of the Skull Base. J Neur Surg B Skull Base. 2016; 77(S 01):P022.
  • Hunter KW, Bai L, Yang HH, Hu Y, Shukla A, Ha NH, Doran, Faraji F, Goldberger, Lee MP, Keane T. Abstract IA21: An integrated genome-wide systems genetics screen for breast cancer metastasis susceptibility genes. Cancer Res. 2016; 76(7 Suppl):IA21.
  • Faraji F, Hu Y, Hunter KW. Mechanistic dissection of the CCR4-NOT complex as a driver of tumor metastasis. Clin Exp Metastasis. 2015; 32(3):201.
  • Faraji F, Hu Y, Goldberger NE, Wu G, Buetow K, Zhang J, Hunter KW. microRNA sequencing of the AKXD recombinant inbred panel identifies miR-216b as a candidate metastasis suppressor in a murine model of breast cancer. Cancer Res. 2012 72(2 Suppl):