American Head & Neck Society

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Chris Holsinger – Palo Alto California

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Chris Holsinger

Stanford University

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875 Blake Wilbur Drive
Stanford Cancer Center, CC-2227
Palo Alto, California 94304
United States
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Dr. Chris Holsinger is Professor and Chief of Head and Neck Surgery at Stanford University.

From 2003-2013, Dr. Holsinger worked at the Department of Head and Neck Surgery at the University of Texas M.D. Anderson Cancer Center where he founded and led the Program in Minimally Invasive and Endoscopic Head and Neck Surgery and co-directed the program in Minimally Invasive Technology in Oncologic Surgery.

In 2013, Dr. Holsinger moved to Stanford University, where at the Cancer Center led H&N Multidisciplinary Cancer Care Clinical Program for the next 5 years. Dr. Holsinger’s surgical practice focuses on the surgical management of thyroid as well as head and neck cancer. His areas of research interest include endoscopic head and neck surgery, including transoral robotic surgery and transoral laser microsurgery, as well as time-honoured approaches of conservation laryngeal surgery and supracricoid partial laryngectomy.

Dr Holsinger's research focuses on surgical innovation and clinical trials. He serves as surgical principal investigator for RTOG920 and coordinated surgeon-credentialing for ECOG 3311, a prospective clinical trial to study robotic head and neck surgery. He recently led an investigative device exemption trial to evaluate the safety and efficacy of a next-generation flexible robotic surgical system which led to FDA approval of the Single-Port Robot in March 2019.

 

His interests extend beyond robotics, however, and include new technologies for augmenting the vision of surgeons and incorporating machine learning and AI into routine surgical practice.    Current algorithms in computer vision and pattern recognition have transformed how we interact with the world using our smart phones. His lab aims to deliver these advantages to patient and their surgeons by providing real-time intelligence about surgical anatomy that extends beyond human vision. In the lab, he is studying multispectral and hyperspectral sensors and machine-learning algorithms to improve and develop novel technologies in surgical vision.  In 2016, he began a prospective clinical trial to evaluate multispectral imaging of patients with oropharyngeal cancer, in an effort to discern tumor from tumor, as well as to evaluate hyper-spectral imaging to improve surgical vision.      In 2017,  he founded Surgical Vision Technologies to translate recent innovations into practice for open surgery.

 

Dr. Holsinger received his medical degree from Vanderbilt School of Medicine, completed his internship and residency at Baylor College of Medicine and his Fellowship in head and neck surgical oncology at The University of Texas M. D. Anderson Cancer Center. In 2003, he was awarded Fulbright Scholarship to study surgery at the University of Paris with Professor Ollivier Laccourreye and with Professor Wolfgang Steiner at the Georg-August University in Göttingen.

Board-certified by the American Board of Otolaryngology, Dr. Holsinger is a member of numerous societies including the American College of Surgeons, American Head and Neck Society, the American Thyroid Association, and the American Society of Clinical Oncology.

 

 

Robotic Head & Neck Surgery Registry

NRG HN005

Evaluating Prognostic Biomarkers in Patients with Oropharyngeal Cancers

 

Peer-Reviewed Original Research Articles

  1. Biggs VJ, Dummer S, Holsinger FC, Loyd JE, Christman BW, Frist WH. Successful treatment of invasive bronchial aspergillosis after single-lung transplantation. Clin Infect Dis 1994; 18(1):123-4.
  2. Kuppersmith RB, Holsinger FC, Jenkins HA. The use of e-mail by otolaryngologists. Arch Otolaryngol Head Neck Surg 1996; 122(9):921-2.
  3. Jewett BS, Holsinger FC, Kuppersmith RB, Buenting JE. Computer-based physician education. Otolaryngol Clin North Am 1998; 31(2):301-7.
  4. Holsinger FC, Coker NJ, Jenkins HA. Hearing preservation in conservation surgery for vestibular schwannoma. Am J Otol 21(5)(5):695-700, 9/2000.
  5. Myers JN, Holsinger FC, Jasser SA, Bekele BN, Fidler IJ. An orthotopic nude mouse model of oral tongue squamous cell carcinoma. Clin Cancer Res 2002; 8(1):293-8.
  6. Holsinger FC, Owens JM, Raymond AK, Myers JN. Central mucoepidermoid carcinoma of the mandible: tumorigenesis within a keratocyst. Arch Otolaryngol Head Neck Surg 2002; 128(6):718-20.
  7. Myers JN, Holsinger FC, Bekele BN, Li E, Jasser SA, Killion JJ, Fidler IJ. Targeted molecular therapy for oral cancer with epidermal growth factor receptor blockade: a preliminary report. Arch Otolaryngol Head Neck Surg 2002; 128(8):875-9.
  8. Diaz EM, Holsinger FC, Zuniga ER, Roberts DB, Sorensen DM. Squamous cell carcinoma of the buccal mucosa: one institution's experience with 119 previously untreated patients. Head Neck 2003; 25(4):267-73.
  9. Holsinger FC, Doan DD, Jasser SA, Swan EA, Greenberg JS, Schiff BA, Bekele BN, Younes MN, Bucana CD, Fidler IJ, Myers JN. Epidermal growth factor receptor blockade potentiates apoptosis mediated by Paclitaxel and leads to prolonged survival in a murine model of oral cancer. Clin Cancer Res 2003; 9(8):3183-9.
  10. Swan EA, Jasser SA, Holsinger FC, Doan D, Bucana C, Myers JN. Acquisition of anoikis resistance is a critical step in the progression of oral tongue cancer. Oral Oncol 2003; 39(7):648-55.
  11. Curino A, Patel V, Nielsen BS, Iskander AJ, Ensley JF, Yoo GH, Holsinger FC, Myers JN, El-Nagaar A, Kellman RM, Shillitoe EJ, Molinolo AA, Gutkind JS, Bugge TH. Detection of plasminogen activators in oral cancer by laser capture microdissection combined with zymography. Oral Oncol 2004; 40(10):1026-32.
  12. Schiff BA, McMurphy AB, Jasser SA, Younes MN, Doan D, Yigitbasi OG, Kim S, Zhou G, Mandal M, Bekele BN, Holsinger FC, Sherman SI, Yeung SC, El-Naggar AK, Myers JN. Epidermal growth factor receptor (EGFR) is overexpressed in anaplastic thyroid cancer, and the EGFR inhibitor gefitinib inhibits the growth of anaplastic thyroid cancer. Clin Cancer Res 2004; 10(24)(24):8594-602.
  13. Laccourreye O, Holsinger FC. A simple method to expose the surgical field when performing a thyroplasty. Otolaryngol Head Neck Surg 2005; 132(1):108-9.
  14. Clayman GL, Lee JJ, Holsinger FC, Zhou X, Duvic M, El-Naggar AK, Prieto VG, Altamirano E, Tucker SL, Strom SS, Kripke ML, Lippman SM. Mortality risk from squamous cell skin cancer. J Clin Oncol 2005; 23(4):759-65.
  15. Moore BA, Holsinger FC, Diaz EM, Weber RS. Organ-preservation laryngeal surgery in the era of chemoradiation. Curr Probl Cancer 2005; 29(4):169-79.
  16. Holsinger FC, McWhorter AJ, Ménard M, Garcia D, Laccourreye O. Transoral lateral oropharyngectomy for squamous cell carcinoma of the tonsillar region: I. Technique, complications, and functional results. Arch Otolaryngol Head Neck Surg 2005; 131(7):583-91.
  17. Laccourreye O, Hans S, Ménard M, Garcia D, Brasnu D, Holsinger FC. Transoral lateral oropharyngectomy for squamous cell carcinoma of the tonsillar region: II. An analysis of the incidence, related variables, and consequences of local recurrence. Arch Otolaryngol Head Neck Surg 2005; 131(7):592-9.
  18. Laccourreye O, El Sharkawy L, Holsinger FC, Hans S, Ménard M, Brasnu D. Thyroplasty type I with Montgomery implant among native French language speakers with unilateral laryngeal nerve paralysis. Laryngoscope 2005; 115(8):1411-7.
  19. Moore BA, Weber RS, Prieto V, El-Naggar A, Holsinger FC, Zhou X, Lee JJ, Lippman S, Clayman GL. Lymph node metastases from cutaneous squamous cell carcinoma of the head and neck. Laryngoscope 2005; 115(9):1561-7.
  20. Yao M, Roebuck JC, Holsinger FC, Myers JN. Elective neck dissection during salvage laryngectomy. Am J Otolaryngol 2005; 26(6):388-92.
  21. Holsinger FC, Laccourreye O, Weinstein GS, Diaz EM, McWhorter AJ. Technical refinements in the supracricoid partial laryngectomy to optimize functional outcomes. J Am Coll Surg 2005; 201(5):809-20.
  22. Holsinger FC, Prichard CN, Shapira G, Weisberg O, Torres DS, Anastassiou C, Harel E, Fink Y, Weber RS. Utility of photonic band gap fiber assembly CO2 laser system in head and neck surgical oncology. Laryngoscope 2006; 116(7):1288-90.
  23. Holsinger FC, Motamed M, Garcia D, Brasnu D, Ménard M, Laccourreye O. Resection of selected invasive squamous cell carcinoma of the pyriform sinus by means of the lateral pharyngotomy approach: the partial lateral pharyngectomy. Head Neck 2006; 28(8):705-11.
  24. Holsinger FC, Funk E, Roberts DB, Diaz EM. Conservation laryngeal surgery versus total laryngectomy for radiation failure in laryngeal cancer. Head Neck 2006; 28(9):779-84.
  25. Laccourreye O, Ménard M, Behm E, Garcia D, Cauchois R, Holsinger FC. Sternocleidomastoid myofascial flap for reconstruction after composite resection of invasive squamous cell carcinoma of the tonsillar region: technique and outcome. Laryngoscope 2006; 116(11):2001-6.
  26. Holsinger FC, Diaz EM. Laryngeal Preservation in the Era of Chemoradiation: Limitations of the Current AJCC Staging System. Head Neck 2006; 28(12):1058-60.
  27. Thompson MA, Habra MA, Routbort MJ, Holsinger FC, Perrier ND, Waguespack SG, Rodriguez MA. Primary adrenal natural killer/T-cell nasal type lymphoma: first case report in adults. Am J Hematol 2007; 82(4):299-303.
  28. O'Daniel JC, Rosenthal DI, Garden AS, Barker JL, Ahamad A, Ang KK, Asper JA, Blanco AI, de Crevoisier R, Holsinger FC, Patel CB, Schwartz DL, Wang H, Dong L. The effect of dental artifacts, contrast media, and experience on inter-observer contouring variations in head and neck anatomy. Am J Clin Oncol 2007; 30(2):191-8.
  29. Hanna EY, Holsinger FC, DeMonte F, Kupferman M. Robotic Endoscopic Surgery of the Skull Base: A Novel Surgical Approach. Arch Otolaryngol Head Neck Surg 2007; 133(12):1209-14.
  30. Holsinger FC, Weber RS. Swing of the surgical pendulum: a return to surgery for treatment of head and neck cancer in the 21st century? Int J Radiat Oncol Biol Phys 2007; 69(2 Suppl):S129-31.
  31. Ark N, Zemo S, Nolen D, Holsinger FC, Weber RS. Management of Locally Invasive Well-Differentiated Thyroid Cancer. Surg Oncol Clin N Am 2008 17(1):145-55.
  32. Holsinger FC, Kies MS, Weinstock YE, Lewin JS, Hajibashi S, Nolen DD, Weber R, Laccourreye O. Videos in Clinical Medicine. Examination of the Larynx and Pharynx. N Engl J Med 2008; 358 (3):e2.
  33. Anaya DA, Holsinger FC, Perrier, ND. Parathyroid Preservation and Autografting in Thyroid Surgery. Curr Probl Surg 2008; 45(3):220-226.
  34. Grubbs EG, Rich TA, Li G, Sturgis EM, Younes MN, Myers JN, Edeiken-Monroe B, Fornage BD, Monroe DP, Staerkel GA, Williams MD, Waguespack SG, Hu MI, Cote G, Gagel RF, Cohen J, Weber RS, Anaya DA, Holsinger FC, Perrier ND, Clayman GL, Evans DB. Recent advances in thyroid cancer. Curr Probl Surg 2008; 45(3):156-250.
  35. Holsinger FC. Swing of the pendulum: optimizing functional outcomes in larynx cancer. Curr Oncol Rep 2008; 10(2):170-175.
  36. Lewin JS, Hutcheson KA, Barringer DA, May AH, Roberts DB, Holsinger FC, Diaz EM. Functional analysis of swallowing outcomes after supracricoid partial laryngectomy. Head Neck 2008; 30(5):559-66.
  37. Laccourreye L, Garcia D, Ménard M, Brasnu D, Laccourreye O, Holsinger FC. Horizontal Supraglottic Partial Laryngectomy for Selected Squamous Carcinoma of the Vallecula. Head Neck 2008; 20(6):756-64.
  38. Thariat J, Ahamad A, El-Naggar AK, Williams MD, Holsinger FC, Glisson BS, Allen PK, Morrison WH, Weber RS, Ang KK, Garden AS. Outcomes after radiotherapy for basaloid squamous cell carcinoma of the head and neck: a case-control study. Cancer 2008; 112(12):2698-709.
  39. McGuff HS, Heim-Hall J, Holsinger FC, Jones AA, O'Dell DS, Hafemeister AC. Maxillary osteosarcoma associated with a dental implant: report of a case and review of the literature regarding implant-related sarcomas. J Am Dent Assoc 2008; 139(8):1052-9.
  40. Holsinger FC, Kies MS, Diaz EM, Gillenwater AM, Lewin JS, Ginsberg LE, Glisson BS, Garden AS, Ark N, Lin HY, Lee JJ, El-Naggar AK, Ki Hong W, Shin DM, Khuri FR. Durable long-term remission with chemotherapy alone for stage II to IV laryngeal cancer. J Clin Oncol 2009; 27(12):1976-82.
  41. Laccourreye O, Seccia V, Ménard M, Garcia D, Vacher C, Holsinger FC. Extended lateral pharyngotomy for selected squamous cell carcinomas of the lateral tongue base. Ann Otol Rhinol Laryngol 2009; 118(6):428-34.
  42. Holsinger FC, Nussenbaum B, Nakayama M, Saraiya S, Sewnaik A, Ark N, Ferris RL, Tufano RP, McWhorter AJ. Current concepts and new horizons in conservation laryngeal surgery: An important part of multidisciplinary care. Head Neck 2009.
  43. Kuppersmith RB, Salem A, Holsinger FC. Advanced approaches for thyroid surgery. Otolaryngol Head Neck Surg 2009; 141(3):340-2.
  44. Holsinger FC, Lin HY, Bassot V, Laccourreye O. Platin-based exclusive chemotherapy for selected patients with squamous cell carcinoma of the larynx and pharynx. Cancer 2009; 115(17):3909-18.
  45. Kupferman M, Demonte F, Holsinger FC, Hanna E. Transantral robotic access to the pituitary gland. Otolaryngol Head Neck Surg 2009; 141(3):413-5.
  46. LeBert B, McWhorter AJ, Kunduk M, Walvekar RR, Lewin JS, Hutcheson KA, Barringer DA, Hessel AC, Holsinger FC. Secondary tracheoesophageal puncture with in-office trans-nasal esophagoscopy. Arch Otolaryngol Head Neck Surg 2009; 135(12):1190-4.
  47. Nakayama M, Holsinger FC, Okamoto M, Seino Y, Miyamoto S, Takeda M, Yokobori S, Masaki T, Hayashi S. Clinicopathological Analyses of Fifty Supracoid Laryngectomized Specimens: Evidence Base Supporting Minimal Margins. ORL J Otorhinolaryngol Relat Spec 2009; 71(6):305-311.
  48. Lewis CM, Chung WY, Holsinger FC. Feasibility and surgical approach of transaxillary robotic thyroidectomy without CO(2) insufflation. Head Neck 2010; 32(1):121-6.
  49. Kies MS, Holsinger FC, Lee JJ, William WN, Glisson BS, Lin HY, Lewin JS, Ginsberg LE, Gillaspy KA, Massarelli E, Byers L, Lippman SM, Hong WK, El-Naggar AK, Garden AS, Papadimitrakopoulou V. Induction chemotherapy and cetuximab for locally advanced squamous cell carcinoma of the head and neck: results from a phase II prospective trial. J Clin Oncol 2010; 28(1):8-14.
  50. Selber JC, Robb G, Serletti JM, Weinstein G, Weber RS, Holsinger FC. Transoral robotic free flap reconstruction of oropharyngeal defects: a preclinical investigation. Plast Reconstr Surg 2010; 125(3):896-900.
  51. Holsinger FC, Terris DJ, Kuppersmith RB. Robotic thyroidectomy: operative technique using a transaxillary endoscopic approach without CO2 insufflation. Otolaryngol Clin North Am 2010; 43(2):381-8.
  52. Kupferman ME, Jiffar T, El-Naggar A, Yilmaz T, Zhou G, Xie T, Feng L, Wang J, Holsinger FC, Yu D, Myers JN. TrkB induces EMT and has a key role in invasion of head and neck squamous cell carcinoma. Oncogene 2010; 29(14):2047-59.
  53. Holsinger FC, Nussenbaum B, Nakayama M, Saraiya S, Sewnaik A, Ark N, Ferris RL, Tufano RP, McWhorter AJ. Current concepts and new horizons in conservation laryngeal surgery: an important part of multidisciplinary care. Head Neck 2010; 32(5):656-65.
  54. Holsinger FC, Sweeney AD, Jantharapattana K, Salem A, Weber RS, Chung WY, Lewis CM, Grant DG. The emergence of endoscopic head and neck surgery. Curr Oncol Rep 2010; 12(3):216-22.
  55. Byers LA, Holsinger FC, Kies MS, William WN, El-Naggar AK, Lee JJ, Hu J, Lopez A, Tran HT, Yan S, Du Z, Ang KK, Glisson BS, Raso MG, Wistuba II, Myers JN, Hong WK, Papadimitrakopoulou V, Lippman SM, Heymach JV. Serum signature of hypoxia-regulated factors is associated with progression after induction therapy in head and neck squamous cell cancer. Mol Cancer Ther 2010; 9(6):1755-1763.
  56. Rosenthal DI, Fuller CD, Barker JL, Mason B, Garcia JA, Lewin JS, Holsinger FC, Stasney CR, Frank SJ, Schwartz DL, Morrison WH, Garden AS, Ang KK. Simple Carotid-Sparing Intensity-Modulated Radiotherapy Technique and Preliminary Experience for T1-2 Glottic Cancer. Int J Radiat Oncol Biol Phys 77(2):455-461, 6/2010
  57. Bhayani MK, Holsinger FC, Lai SY. A shifting paradigm for patients with head and neck cancer: transoral robotic surgery (TORS). Oncology (Williston Park) 24(11):1010-1015, 10/2010.
  58. Holsinger FC, Hafemeister AC, Hicks MJ, Sulek M, Huh WW, Friedman EM. Differential diagnosis of pediatric tumors of the nasal cavity and paranasal sinuses: a 45-year multi-institutional review. Ear Nose Throat J 2010; 89(11):534-540.
  59. Schwartz DL, Hutcheson K, Barringer D, Tucker SL, Kies M, Holsinger FC, Ang KK, Morrison WH, Rosenthal DI, Garden AS, Dong L, Lewin JS. Candidate Dosimetric Predictors of Long-Term Swallowing Dysfunction After Oropharyngeal Intensity-Modulated Radiotherapy. Int J Radiat Oncol Biol Phys 2010 78(5):1356-1365.
  60. Bell D, Holsinger FC, El-Naggar AK. CRTC1/MAML2 fusion transcript in central mucoepidermoid carcinoma of mandible--diagnostic and histogenetic implications. Ann Diagn Pathol 2010; 14(6):396-401.
  61. Lewis CM, Hessel AC, Roberts DB, Guo YZ, Holsinger FC, Ginsberg LE, El-Naggar AK, Weber RS. Prereferral head and neck cancer treatment: compliance with national comprehensive cancer network treatment guidelines. Arch Otolaryngol Head Neck Surg 2010; 136(12):1205-1211.
  62. Seybt M, Kuppersmith RB, Holsinger FC, Terris DJ. Robotic Axillary Thyroidectomy: Multi-Institutional Clinical Experience with the daVinci. Laryngoscope 2010; 120(Supplement S4):S182.
  63. Simon C, El-Baba B, Albrecht T, Holsinger, FC, Plinkert PK. First Experience in Germany with Transoral Robotic Surgery. HNO 2011; 59(3):261-265.
  64. Kuppersmith RB, Holsinger FC. Robotic Thyroid Surgery: An Initial Experience with North American Patients. Laryngoscope 2011; 121(3):521-526.
  65. Landry CS, Grubbs EG, Morris GS, Turner NS, Holsinger FC, Lee JE, Perrier ND. Robot assisted transaxillary surgery (RATS) for the removal of thyroid and parathyroid glands. Surgery 2011; 149(4):549-555.
  66. Benito J, Holsinger FC, Perez-Martin A, Garcia D, Weinstein GS, Laccourreye O. Aspiration after Supracricoid Partial Laryngectomy: Incidence, Risk Factors, Management, and Outcomes. Head Neck 2011; 33(5):679-685.
  67. Kandil E, Noureldine S, Abdel Khalek M, Alrasheedi S, Aslam R, Friedlander P, Holsinger FC, Bellows CF. Initial experience using robot- assisted transaxillary thyroidectomy for Graves' disease. J Visc Surg 2011; 148(6):e447-451.
  68. Richmon JD, Holsinger FC, Kandil E, Moore MW, Garcia JA, Tufano RP. Transoral robotic-assisted thyroidectomy with central neck dissection: preclinical cadaver feasibility study and proposed surgical technique. J Robot Surg 2011; 5(4):279-282.
  69. Nakayama M, Laccourreye O, Holsinger FC, Okamoto M, Hayakawa K. Functional organ-preservation for laryngeal cancer: Past, present, and future. Jpn J Clin Oncol 2012; 42(3):155-160.
  70. Selber JC, Baumann DP, Holsinger FC. Robotic Latissimus Dorsi Muscle Harvest: A Case Series. Plast Reconstr Surg 2012; 129(6):1305-1312.
  71. Kandil E, Noureldine S, Abdel Khalek M, Aslam R, Ekaidi I, Steiner R, Holsinger FC. Robotic transaxillary thyroidectomy with gasless approach in a girl with goitre. Int J Med Robot 2012 8(2):210-214.
  72. Huh WW, Holsinger FC, Levy A, Palla FS, Anderson PM. Osteosarcoma of the Jaw in Children and Young Adults. Head Neck 2011; 34(7):981-984.
  73. Weinstein GS, O'Malley BW, Magnuson JS, Carroll WR, Olsen KD, Daio L, Moore EJ, Holsinger FC. Transoral robotic surgery: A multicenter study to assess feasibility, safety, and surgical margins. Laryngoscope 2012; 122(8):1701-1707.
  74. Longfield EA, Holsinger FC, Selber JC. Reconstruction after Robotic Head and Neck Surgery: When and Why. J Reconstr Microsurg 2012; 28(7):445-450.
  75. Selber JC, Baumann DP, Holsinger FC. Robotic Harvest of the Latissimus Dorsi Muscle: Laboratory and Clinical Experience. J Reconstr Microsurg 2012; 28(7):457-464.
  76. Lohavanichbutr P, Houck J, Doody DR, Wang P, Mendez E, Futran N, Upton MP, Holsinger FC, Schwartz SM, Chen C. Gene expression in uninvolved oral mucosa of OSCC patients facilitates identification of markers predictive of OSCC outcomes. PLoS One 2012; 7(9):e46575.
  77. Holsinger FC. Functional and Oncologic Outcomes of Primary versus Salvage Transoral Laser Microsurgery for Supraglottic Carcinoma. Annals of Otology, Rhinology & Laryngology.  2012; 121(10):664-670.
  78. Laccourreye O, Malinvaud D, Holsinger FC, Consoli S, Ménard M, Bonfils P. Trade-off between Survival and Laryngeal Preservation in Advanced Laryngeal Cancer: The Patient’s Perspective. Ann Otol Rhinol Laryngol. 2012; 121(9):570-575.
  79. Lohavanichbutr P, Méndez E, Holsinger FC, Rue TC, Zhang Y, Houck J, Upton MP, Futran N, Schwartz SM, Wang P, A 13-Gene Signature Prognostic of HPV-Negative OSCC: Discovery and External Validation. Chen C. Clinical Cancer Res. 2013; 19(5):1197-1203.
  80. Adelstein DJ, Ridge JA, Brizel DM, Holsinger FC, Haughey BH, O'Sullivan B, Genden EM, Beitler JJ, Weinstein GS, Quon H, Chepeha DB, Ferris RL, Weber RS, Movsas B, Waldron J, Lowe V, Ramsey S, Manola J, Yueh B, Carey TE, Bekelman JE, Konski AA, Moore E, Forastiere A, Schuller DE, Lynn J, Ullmann CD. Transoral resection of pharyngeal cancer: summary of a National Cancer Institute Head and Neck Cancer Steering Committee Clinical Trials Planning Meeting, November 6-7, 2011. Head Neck. 2012; 34(12):1681-1703.
  81. Holsinger FC, Phia-Paul SA, Janku F, Hong DS. Atkins JT, Tsimberidou AM, Kurzrock R. Biomarker-Directed Therapy of Squamous Carcinomas of the Head and Neck: Targeting the PI3K/PTEN/mTOR Pathway. Journal of Clinical Oncology 2013; 31(9): 137-140.
  82. Hutcheson Ka, Lewin JS, Barringer DA, Lisec A, Gunn GB, Moore MWS, Holsinger FC. Late Dysphagia after Radiotherapy-Based Treatment of Head and Neck Cancer. 2012 118(23): 5793-99.
  83. Laccourreye O, Malinvaud D, Alzahrani H, Ménard M, Garcia D,Bonfils P, Holsinger FC. Conventional Transoral Resection of Selected T1-2 N0 M0 Squamous Cell Carcinoma of the Tonsillar Region. Head & Neck. 2013; 35(5):653-659.
  84. White H, Ford S, Bush B, Holsinger FC, Moore E, Ghanem T, Carroll W, Rosenthal E, Magnuson JS. Salvage Surgery for Recurrent Cancers of the Oropharynx: Comparing TORS with Standard Open Surgical Approaches. JAMA Otolaryngol Head Neck Surg. 2013; 139(8):773-778.
  85. Laccourreye O, Benito J, Menard M, Garcia D, Malinvaud D, Holsinger FC. Lateral pharyngotomy for selected invasive squamous cell carcinoma of the lateral oropharynx--part I: how. Laryngoscope. 2013; 123(11):2712-2717.
  86. Laccourreye O, Benito J, Garcia D, Menard M, Bonfils P, Holsinger FC. Laryngoscope. Lateral Pharyngotomy for Selected Cancer of the Lateral Oropharynx. Part II: When and Why. 2013; 123(11):2718-2722.
  87. Park YM, Holsinger FC, Kim WS, et al. Robot-assisted selective neck dissection of levels II to V via a modified facelift or retroauricular approach. Otolaryngol Head Neck Surg. 2013; 148(5):778-785.
  88. Patel SA, Magnuson JS, Holsinger FC, et al. Robotic Surgery for Primary Head and Neck Squamous Cell Carcinoma of Unknown Site. JAMA Otolaryngol Head Neck Surg 2013;139(11):1203-1211
  89. Byeon HK, Holsinger FC, Koh YW, Ban MJ, Ha JG, Park JJ, Kim D, Choi EC. Endoscopic supraomohyoid neck dissection via a retroauricular or modified facelift approach: Preliminary results. Head Neck. 2014. 36(3):425-430.
  90. Bell D, Holsinger FC, Ordonez N, El-Naggar AK. Intestinal-type adenocarcinoma of the larynx: Report of a rare aggressive phenotype and discussion of histogenesis. Head Neck 2014; 36(5):E44-47.
  91. Loyo M, Laccourreye O, Weinstein GS, Holsinger FC. Corniculate reconstruction after arytenoid resection in supracricoid laryngectomy. Laryngoscope 2014; 124(2):472-475.
  92. White H, Ford S, Bush B, Holsinger FC, et al. Salvage surgery for recurrent cancers of the oropharynx: comparing TORS with standard open surgical approaches. JAMA Otolaryngol Head Neck Surg 2013; 139(8):773-778.
  93. Hutcheson KA, Lewin JS, Holsinger FC, Steinhaus G, Lisec A, Barringer DA, Lin HY, Villalobos S, Garden AS, Papadimitrakopoulou V, Kies MS. Long-term functional and survival outcomes after induction chemotherapy and risk-based definitive therapy for locally advanced squamous cell carcinoma of the head and neck. Head & Neck 2014; 36(4):474-480.
  94. Byeon HK, Holsinger FC, Tufano RP, Chung HJ, Kim WS, Koh YW, Choi EC. Robotic Total Thyroidectomy with Modified Radical Neck Dissection via Unilateral Retroauricular Approach. Ann Surg Oncol 2014; 21(12):3872-5.
  95. Murillo–Sauca O, Chung MK, Shin JH, Karamboulas C, Kwok S, Jung YH, Oakley R, Tysome JR, Farnebo LO, Kaplan MJ, Sirjani D, Divi V, Holsinger FC, Tomeh C, Nichols A, Le QT, Colevas AD, Kong CS, Uppaluri R, Lewis JS Jr, Ailles LE, Sunwoo JB. CD271 is a functional and targetable marker of tumor-initiating cells in head and neck squamous cell carcinoma.  Oncotarget 2014; 16(9):876-88.
  96. Awan Mj, Mohamed AS, Lewin JS, Baron CA, Gunn GB, Rosenthal DI, Holsinger FC, Schwartz DL, Fuller CD, Hutcheson KA. Late radiation-associated dysphagia (late-RAD) with lower cranial neuropathy after oropharyngeal radiotherapy: a preliminary dosimetric comparison. Oral Oncol 2014; 50(8):746-52.
  97. Selber JC, Sarhane KA, Ibrahim AE, Holsinger FC. Transoral robotic reconstructive surgery. Semin Plast Surg 2014; 28(1):35-8.
  98. Holsinger FC, Ramaswamy U, Cabanillas ME, Lang J, Lin HY, Busaidy NL, Grubbs E, Rahim S, Sturgis EM, Lee JE, Weber RS, Clayman GL, Rohren EM. Measuring the extent of total thyroidectomy for differentiated thyroid carcinoma using radioactive iodine imaging: relationship with serum thyroglobulin and clinical outcomes. JAMA Otolaryngology Head Neck Surg 2014; 140(5):410-5.
  99. Hutcheson KW, Holsinger FC, Kupferman ME, Lewin JS. Functional outcomes after TORS for oropharyngeal cancer: a systematic review. Eur Arch Otorhinolaryngol 2015; 272(2):463-471.
  100. Roman BR, Patel SG, Wang MB, Pou AM, Holsinger FC, Myssiorek D, Goldenberg D, Swisher-McClure S, Lin A, Shah JP, Shea JA. Guideline familiarity predicts variation in self-reported use of routine surveillance PET/CT by physicians who treat head and neck cancer. J Natl Compr Canc Netw. 2015; 13(1):69-77.
  101. Byeon HK, Holsinger FC, Kim DH, Kim JW, Park JH, Koh YW, Choi EC. Feasibility of robot-assisted neck dissection followed by transoral robotic surgery. Br J Oral Maxillofac Surg 2015; 53(1):68-73
  102. Holsinger FC, Tomeh C, Moor MW, Yan W, Chen C, Laccourreye O. Head Neck. Supracricoid   Partial Laryngectomy with Cricohyoidoepiglottopexy: Surgical Technique Illustrated in the Anatomy Lab.   Head Neck  2015; 37(6):906-8.
  103. Lee HY, Richmon JD, Walvekar RR, Holsinger FC, Kim HY. Robotic transoral periosteal thyroidectomy: experience in two cadavers. J Laparoendosc Adv Surg Tech A 2015; 25(2):139-42.
  104. Garas G, Holsinger FC, Grant DG, Athanasiou T, Arora A, Tolley N. Is robotic parathyroidectomy a feasible and safe alternative to targeted open parathyroidectomy for the treatment of primary hyperparathyroidism? Int J Surg 2015; 15:55-60.
  105. Zeidan YH, Pekelis L, An Y, Holsinger FC, Kong CS, Chang DT, Le QT. Survival benefit for adjuvant radiation therapy in minor salivary gland cancers. Oral Oncol 2015; 51(5):438-45.
  106. Hutcheson KA, Yuk MM, Holsinger FC, Gunn GB, Lewin JS. Late radiation-associated dysphagia (late-RAD) with lower cranial neuropathy in long-term oropharyngeal cancer survivors: Video case reports. Head Neck 2015; 37(4):E56-62.
  107. Laccourreye O, Werner A, McGill I, Holsinger FC. Clar as Mud? Origins of the Head Mirror: A Historical Note. Head Neck [Epub ahead of print] 2015 Apr 27. doi: 10.1002/hed.24093
  108. Shaw RJ, Holsinger FC, Paleri V, Evans M, Tudur-Smith C, Ferris RL. Surgical trials in head and neck oncology: Renaissance and revolution? Head Neck 2015; 37(7):927-30.
  109. McClary AC, West RB, McClary AC, Pollack JR, Fischbein NJ, Holsinger FC, Sunwoo J, Colevas AD, Sirjani D. Ameloblastoma: a clinical review and trends in management. Eur Arch Otorhinolaryngol 2015. Apr 30. [Epub ahead of print]
  110. de Almeida JR, Li RJ, Magnuson JS, Smith RV, Moore EJ, Lawson G, Remacle M, Ganly I, Kraus DH, Teng MS, Miles Brett A, White H, Duvvuri U, Ferris RL, Mehta V, Kiyosaki K, Damrose EJ, Wang SJ, Kupferman ME, Koh YW, Genden EM, Holsinger FC.    Oncologic Outcomes following Transoral Robotic Surgery (TORS): A Multi-Institutional Study.  JAMA Otolaryngol Head Neck Surg. 2015; 141(12):1043-1051.
  111. Holsinger FC. Ferris RL.  Transoral Endoscopic Head and Neck Surgery and Its Role Within the Multidisciplinary Treatment Paradigm of Oropharynx Cancer:  Robotics, Lasers, and Future Innovations.  J Clin Oncol 2015; 10;33(29):3285-92.
  112. Tsang RK, Sorger JM, Azizian M, Holsinger FC. Real-time navigation in transoral robotic nasopharyngectomy utilizing on table fluoroscopy and image overlay software: a cadaveric feasibility study. J Robot Surg. 2015;9(4):311-314.
  113. Byeon HK, Holsinger FC, Tufano RP, Park JH, Sim NS, Kim WS, Choi EC, Koh YW. Endoscopic retroauricular thyroidectomy: preliminary results. Surg Endosc 2016. 30(1):355-65.
  114. Mudry A, Holsinger FC, Rameau A. Origins of the binocular head mirror: The mystery of Dr. Clar, clarified. Int J Pediatr Otorhinolaryngol. 2016; 80:101-5.
  115. Holsinger FC. A Flexible, Single-Arm, Robotic Surgical System for Transoral Resection of the Tonsil, Lateral Pharyngeal Wall: Next-Generation Robotic Head and Neck Surgery.  Laryngoscope 2016; 126(4):864-9.
  116. Beswick DM, Vashi A, Song Y, Pham R, Holsinger FC et al. Consultation via telemedicine and access to operative care for patients with head and neck cancer in a Veterans Health Administration population. Head & Neck. 2016;  126(9):1977-80.
  117. Roberts TJ, Colevas AD, Hara W, Holsinger FC, Oakley-Girvan I, Divi V. Number of positive nodes is superior to the lymph node ratio and American Joint Committee on Cancer N staging for the prognosis of surgically treated head and neck squamous cell carcinomas. Cancer 2016; 122(9):1388-97
  118. Gross ND, Holsinger FC, Magnuson JS, Duvvuri U, Genden EM, Ghanem TA, Yaremchuk KL, Goldenberg D, Miller MC, Moore EJ, Morris G, Netterville J, Weinstein GS, Richmon J. Robotics in otolaryngology and head and neck surgery: Recommendations for training and credentialing: A report of the 2015 AHNS education committee, AAO-HNS robotic task force and AAO-HNS sleep disorders committee.  Head Neck. 2016; 38 Suppl 1:E151-8.
  119. Chen MM, Holsinger FC. Morbidity and Mortality Associated With Robotic Head and Neck Surgery: An Inquiry of the Food and Drug Administration Manufacturer and User Facility Device Experience Database. JAMA Otolaryngol Head Neck Surg. 2016; 142(4):405-6.
  120. Tsao AS, Papadimitrakopoulou V, Lin H, Guo M, Lee JJ, Holsinger FC, Hong WK, Sturgis EM. Concordance of oral HPV prevalence between patients with oropharyngeal cancer and their partners. Infect Agent Cancer. 2016 [Epub ahead of print] doi: 10.1186/s13027-016-0066-9.
  121. Divi V, Harris J, Harari PM, Cooper JS, McHugh J, Bell D, Sturgis EM, Cmelak AJ, Suntharalingam M, Raben D, Kim H, Spencer SA, Laramore GE, Trotti A, Foote RL, Schultz C, Thorstad WL, Zhang QE, Le QT, Holsinger FC. Establishing quality indicators for neck dissection: Correlating the number of lymph nodes with oncologic outcomes (NRG Oncology RTOG 9501 and RTOG 0234) Cancer. 2016
  122. Tsang RK, Holsinger FC. Transoral endoscopic nasopharyngectomy with a flexiable next-generation robotic surgical system. Laryngoscope 2016; 126(10):2257-62.
  123. Beswick DM, Holsinger FC, Kaplan MJ, Fischbein NJ, Hara W, Colevas AD, Le QT, Berry GJ, Hwang PH. Design and rationale of a prospective, multi-institutional registry for patients with sinonasal malignancy. Laryngoscope Laryngoscope 2016; 126(9):1977-80.
  124. Divi V. Chen MM. Nussenbaum B. Rhoads KF. Sirjani DB. Holsinger FC. Shah JL. Hara WY. Lymph Node Count from Neck Dissection Predicts Mortality in Head and Neck Cancer. Journal of Clinical Oncology 2016; 34(32):3892-3897.
  125. Brennan K, Holsinger FC, Dosiou C, Sunwoo JB, Akatsu H, Haile R, Gevaert O. Development of prognostic signatures for intermediate-risk papillary thyroid cancer. BMC Cancer. 2016;16(1):736.
  126. Duke WS, Holsinger FC, Kandil E, Richmon JD, Singer MC, Terris DJ. Remote Access Robotic Facelift Thyroidectomy: A Multi-institutional Experience. World Jounel of Surgery 2017; 41(1):116-121.
  127. Garas G, Kythreotou A, Georgalas C, Arora A, Kotecha B, Holsinger FC, Grant DG, Tolley N. Is transoral robotic surgery a safe and effective multilevel treatment for obstructive sleep apnoea in obese patients following failure of conventional treatment(s)? Ann Med Surg (Lond). 2017;19:55-61
  128. Starmer HM, Ayoub N, Byward C, Kizner J, Le Q, Hara W, Holsinger FC. The impact of developing a speech and swallow rehab program: Improving patient satisfaction and multidisciplinary care. Laryngoscope. 2017;127(11):2578-2581.
  129. Rubin F, Laccourreye O, Weinstein GS, Holsinger FC. Transoral Lateral Orpharyngectomy. Eur Ann Otorhinolaryngol Hea Neck Dis. 2017 Dec;134(6):419-422.
  130. Chen MY, Orosco RK, Lim GC, Holsinger FC. Improved Transoral Dissection of the Tongue Base With a Next-Generation Robotic Surgical System. Laryngoscope 2018;128(1):78-83.
  131. Tateya I, Koh YW, Tsang RK, Hong SS, Uozumi R, Kishimoto Y, Sugimoto T, Holsinger FC. Flexible next-generation robotic surgical system for transoral endoscopic hypopharyngectomy: A comparative preclinical study. Head & Neck 2018; 40(1):16-23.
  132. Byeon HK, Holsinger FC, Duvvuri U, Kim DH, Park JH, Chang E, Kim SH, Koh YW. Recent progress of retroauricular robotic thyroidectomy with the new surgical robotic system. Laryngoscope. 2017 Oct 25. doi: 10.1002/lary.26938. [Epub ahead of print]
  133. Quon H, Vapiwala N, Forastiere A, Kennedy EB, Adelstein DJ, Boykin H, Califano JA, Holsinger FC, Nussenbaum B, Rosenthal DI, Siu LL, Waldron JN. Radiation Therapy for Oropharyngeal Squamous Cell Carcinoma: American Society of Clinical Oncology Endorsement of the American Society for Radiation Oncology Evidence-Based Clinical Practice Guideline. J Clin Oncol. 2017;  35(36) :4078-4090.
  134. Starmer HM, Abrams R, Webster K, Kizner J, Beadle B, Holsinger FC, Quon H, Richmon J. Feasibility of a Mobile Application to Enhance Swallowing Therapy for Patients Undergoing Radiation-Based Treatment for Head and Neck Cancer. Dysphagia. 2018 Apr;33(2):227-233.
  135. Chan JYK, Wong EWY, Tsang RK, Holsinger FC, Tong MCF, Chiu PWY, Ng SSM. Early results of a safety and feasibility clinical trial of a novel single-port flexible robot for transoral robotic surgery. Eur Arch Otorhinolaryngol. 2017; 274(11):3993-3996.
  136. Mascharak S, Baird BJ, Holsinger FC. Detecting oropharyngeal carcinoma using multispectral, narrow-band imaging and machine learning. Laryngoscope. 2018 Mar 25. doi: 10.1002/lary.27159.
  137. Heah H, Goepfert RP, Hutcheson KA, Garden AS, Gunn GB, Fuller CD, Lewin JS, Kupferman ME, Holsinger FC, Hessel AC, Gross ND. Decreased gastrostomy tube incidence and weight loss after transoral robotic surgery for low- to intermediate-risk oropharyngeal squamous cell carcinoma.  Head Neck. 2018 Aug 13. doi: 10.1002/hed.25382. [Epub ahead of print]
  138. Gao RW, Teraphongphom NT, van den Berg NS, Martin BA, Oberhelman NJ, Divi V, Kaplan MJ, Hong SS, Lu G, Ertsey R, Tummers WSFJ, Gomez AJ, Holsinger FC, Kong CS, Colevas AD, Warram JM, Rosenthal EL. Determination of Tumor Margins with Surgical Specimen Mapping Using Near-Infrared Fluorescence.  Cancer Res. 2018;78(17):5144-5154.
  139. Laccourreye O, Orosco RK, Rubin F, Holsinger FC. The styloglossus muscle: A critical landmark in oncology.  Eur Ann Otorhinolaryngol Head Neck Dis. 2018 Oct 16. [Epub ahead of print].
  140. Xiang M, Holsinger FC, Colevas AD, Chen MM, Le QT, Beadle BM. Survival of patients with head and neck cancer treated with definitive radiotherapy and concurrent cisplatin or concurrent cetuximab: A Surveillance, Epidemiology, and End Results-Medicare analysis.  2018 Oct 17. doi: 10.1002/cncr.31708. [Epub ahead of print].
  141. Orosco RK, Arora A, Jeanon JP, Holsinger FC. Next-Generation Robotic Head and Neck Surgery. ORL J Otorhinolaryngol Relat Spec. 2018; 80(3-4):213-219.
  142. Howard J, Dwivedi RC, Masterson L, Kothari P, Quon H, Holsinger FC. De-intensified adjuvant (chemo)radiotherapy versus standard adjuvant chemoradiotherapy post transoral minimally invasive surgery for resectable HPV-positive oropharyngeal carcinoma.  Cochrane Database Syst Rev. 2018. 2018 Dec 14;12:CD012939. doi: 10.1002/14651858.CD012939.
  143. Tam K, Orosco RK, Colevas AD, Bedi N, Starmer HM, Beadle BM, Holsinger FC. Cost Comparison of Treatment for Oropharyngeal Carcinoma. Laryngoscope [Epub ahead of print]. doi:10.1002/lary.27544
  144. Finegersh A, Holsinger FC, Gross ND, Orosco RK. Robotic Head and Neck Surgery. Surg Oncol Clin N Am. 2019; 28(1):115-128.
  145. Laccourreye O, Villeneuve A, Rubin F, Holsinger FC. Lateral pharyngotomy.  Eur Ann Otorhinolaryngol Head Neck Dis. 2018 Oct 25.  (18) 30172-8. doi: 10.1016/j.anorl.2018.10.011.
  146. Orosco RK, Tam K, Nakayama M, Holsinger FC, Spriano G. Transoral supraglottic laryngectomy using a next-generation single-port robotic surgical system.  Head Neck. 2019 Feb 18. doi: 10.1002/hed.25676. [Epub ahead of print]
  147. Nakayama M, Holsinger FC, Orosco RK. Hybrid supracricoid partial laryngectomy with cricohyoidoepiglottopexy via transoral robotic surgery. Laryngoscope. 2018 Dec 19. doi: 10.1002/lary.27628. [Epub ahead of print]
  148. Nakayama M, Holsinger FC, Chevalier D, Orosco RK. The dawn of robotic surgery in otolaryngology: head and neck surgery. Jpn J Clin Oncol. 2019 Feb 23. doi: 10.1093/jjco/hyz020.
  149. Koyfman SA, Ismaila N, Crook D, D'Cruz A, Rodriguez CP, Sher DJ, Silbermins D, Sturgis EM, Tsue TT, Weiss J, Yom SS, Holsinger FC. Management of the Neck in Squamous Cell Carcinoma of the Oral Cavity and Oropharynx: ASCO Clinical Practice Guideline.  J Clin Oncol. 2019 Feb 27:JCO1801921. doi: 10.1200/JCO.18.01921.
  150. Xiang M, Colevas AD, Holsinger FC, Le QT, Beadle BM. Survival After Definitive Chemoradiation with Concurrent Cisplatin or Carboplatin for Head and Neck Cancer. J Natl Compr Canc Netw. 2019  [In Press]
  151. Yang TL, Li H, Holsinger FC, Koh YW. Submandibular Gland Resection via the Trans-Hairline Approach: A Preclinical Study of a Novel Flexible Single-Port Surgical System and the Surgical Experiences of Standard Multiarm Robotic Surgical Systems: Head and Neck. 2019 July: doi: 10.1002/hed.25692 [epub 2019 Mar 21]
  152. Yao T, Beadle B, Holsinger FC, Starmer HM. Effectiveness of a Home-based Head and Neck Lymphedema Management Program: A Pilot Study: Laryngoscope. 2020 Feb 18. doi: 10.1002/lary.28549 [ahead of print]
  153. Stokes W, Ramadan J, Lawson G, Ferris FRL,Holsinger FC, Turner MT. Bleeding Complications After Transoral Robotic Surgery: A Meta-Analysis and Systematic Review: Laryngoscope. 2020 Feb 28. doi: 10.1002/lary.28580 [ahead of print]
  154. Ku PKM,Holsinger FC, Chan JYK, Yeung ZWC, Chan BYT, Tong MCF, Starmer HM. Management of Dysphagia in the Patient with Head and Neck Cancer During COVID-19 Pandemic: Practical Strategy. Head & Neck 2020 Apr 29;10.1002/hed.26224. doi: 10.1002/hed.26224 [ahead of print]
  155. Simon C,Holsinger FC, Rheinwald M, Kemper J, Lambercy K. A New Endoscopic Surgical Approach to the Larynx, Hypopharynx, and Neck Lymphatics: The Robotic-Assisted Extended "Sistrunk" Approach (RESA). Head & Neck 2020 Jun 13. doi: 10.1002/hed.26273 [ahead of print]
  156. Martínez JRW, Vargas-Salas S, Gamboa SU, Muñoz E, Domínguez JM, León A, Droppelmann N, Solar A, Zafereo M,Holsinger FC, González HE. The Combination of RET, BRAF and Demographic Data Identifies Subsets of Patients With Aggressive Papillary Thyroid Cancer. Cancer. 2019 Jun;10(2-3):97-106. doi:10.1007/s12672-019-0359-8.
  157. Chan JYK, Tsang RK,Holsinger FC, Tong MCF, Ng CWK, Chiu PWY, Ng SSM, Wong EWY. Prospective Clinical Trial to Evaluate Safety and Feasibility of Using a Single Port Flexible Robotic System for Transoral Head and Neck Surgery. Oral Oncol. 2019 Jul;94:101-105. doi: 10.1016/j.oraloncology.2019.05.018.
  158. Eguchi K, Chan JYK, Tateya I, Shimizu A,Holsinger FC, Sugimoto T. Curved Laryngopharyngoscope With Flexible Next-Generation Robotic Surgical System for Transoral Hypopharyngeal Surgery: A Preclinical Evaluation. Ann Otol Rhinol Laryngol. 2019 Nov;128(11):1023-1029. doi: 10.1177/0003489419856391. Epub
  159. Park YM, Kim DH, Moon YM, Lim JY, Choi EC, Kim SH,Holsinger FC, Koh YW. Gasless Transoral Robotic Thyroidectomy Using the DaVinci SP System: Feasibility, Safety, and Operative Technique. Oral Oncol. 2019 Aug;95:136-142. doi: 10.1016/j.oraloncology.2019.06.003. Epub
  160. Schiff BA, McMurphy AB, Jasser SA, Younes MN, Doan D, Yigitbasi OG, Kim S, Zhou G, Mandal M, Bekele BN,Holsinger FC, Sherman SI, Yeung SC, El-Naggar AK, Myers JN. Editor's Note: Epidermal Growth Factor Receptor (EGFR) Is Overexpressed in Anaplastic Thyroid Cancer, and the EGFR Inhibitor Gefitinib Inhibits the Growth of Anaplastic Thyroid Cancer. Clinical Cancer Res. 2019 Aug. doi: 10.1158/1078-0432.CCR-19-2052.
  161. Holsinger FC, Magnuson JS, Weinstein GS, Chan JYK, Starmer HM, Tsang RKY, Wong EWY, Rassekh CH, Bedi N, Hong SSY, Orosco R, O'Malley BW Jr, Moore EJ. A Next-Generation Single-Port Robotic Surgical System for Transoral Robotic Surgery: Results From Prospective Nonrandomized Clinical Trials. JAMA Otolaryngol Head Neck Surg. 2019 Sep 19;145(11):1027-1034.
  162. Chan JYK,Holsinger FC, Liu S, Sorger JM, Azizian M, Tsang RKY. Augmented Reality for Image Guidance in Transoral Robotic Surgery J Robot Surg 2019 Sep 25. doi: 10.1007/s11701-019-01030-0. [ahead of print]
  163. De Virgilio A, Kim SH, Magnuson JS,Holsinger C, Remacle M, Lawson G, Wang CC, Mercante G, Malvezzi L, Iocca O, Di Maio P, Ferreli F, Pellini R, Spriano G. Anatomical-based Classification for Transoral Lateral Oropharyngectomy. Oral Oncol 2019 Dec.  doi:10.1016/j.oraloncology. 2019.104450. [Epub]
  164. Sato E, Mitani S, Nishio N, Kitani T, Sanada T, Ugumori T, Holsinger FC, Baik FM, Hato N Development of Proficiency-Based Knot-Tying and Suturing Curriculum for Otolaryngology Residents: A Pilot Study. Auris Nasus Larynx 2020 Apr. doi: 10.1016/j.anl.2019.11.005. Epub
  165. Zafereo M, McIver B, Vargas-Salas S, Domínguez JM, Steward DL,Holsinger FC, Kandil E, Williams M, Cruz F, Loyola S, Solar A, Roa JC, León A, Droppelman N, Lobos M, Arias T, Kong CS, Busaidy N, Grubbs EG, Graham P, Stewart J, Tang A, Wang J, Orloff L, Henríquez M, Lagos M, Osorio M, Schachter D, Franco C, Medina F, Wohllk N, Diaz RE, Veliz J, Horvath E, Tala H, Pineda P, Arroyo P, Vasquez F, Traipe E, Marín L, Miranda G, Bruce E, Bracamonte M, Mena N, González HE. A Thyroid Genetic Classifier Correctly Predicts Benign Nodules With Indeterminate Cytology: Two Independent, Multicenter, Prospective Validation Trials. 2020 May. doi: 10.1089/thy.2019.0490. Epub
  166. Roman BR, Lohia S, Mitra N, Wang MB, Pou AM,Holsinger FC, Myssiorek D, Goldenberg D, Asch DA, Shea JA. Perceived Value Drives Use of Routine Asymptomatic Surveillance PET/CT by Physicians Who Treat Head and Neck Cancer. Head Neck 2020 May doi: 10.1002/hed.26071. [Epub]
  167. Chan JYK, Koh YW, Richmon J, Kim J,Holsinger FC, Orloff L, Anuwong A. Transoral Thyroidectomy With a Next Generation Flexible Robotic System: A Feasibility Study in a Cadaveric Model. Gland Surg 2019 Dec.doi: 10.21037/gs.2019.10.13
  168. Vukkadala N, Qian ZJ,Holsinger FC, Patel ZM, Rosenthal E. COVID-19 and the Otolaryngologist: Preliminary Evidence-Based Review. Laryngoscope 2020 Mar 26. doi: 10.1002/lary.28672.
  169. Chan JYK, Tsang RKY, Yeung KW, Abdullah V, Ku P, Wong EWY, Mehta N, Orosco RK,Holsinger FC. There Is No Routine Head and Neck Exam During the COVID-19 Pandemic. Head Neck 2020 Jun. doi: 10.1002/hed.26168. [Epub]
  170. Kligerman MP, Vukkadala N, Tsang RKY, Sunwoo JB,Holsinger FC, Chan JYK, Damrose EJ, Kearney A, Starmer HM. Managing Head and Neck Cancer Patients With Tracheostomy or Laryngectomy During the COVID-19 Pandemic. Head Neck. 2020 Jun. doi: 10.1002/hed.26171. [Epub]
  171. Topf MC, Shenson JA,Holsinger FC, Wald SH, Cianfichi LJ, Rosenthal EL, Sunwoo JB. Framework for Prioritizing Head and Neck Surgery During the COVID-19 Pandemic. Head Neck 2020 Jun. doi: 10.1002/hed.26184. [Epub]
  172. Gupta A, Arora V, Nair D, Agrawal N, Su YX,Holsinger FC, Chan JYK Status and Strategies for the Management of Head and Neck Cancer During COVID-19 Pandemic: Indian Scenario. Head Neck. 2020 May 1. doi: 10.1002/hed.26227 [ahead of print]
  173. Orosco RK, Lurie B, Matsusaki T, Funk EK, Divi V,Holsinger FC, Hong S, Richter F, Das N, Yip M.Compensatory Motion Scaling for Time-Delayed Robotic Surgery. Surg Endosc 2020 Jun 8. doi: 10.1007/s00464-020-07681-7. [ahead of print]
  174. Mehanna H, Hardman JC, Shenson JA, Abou-Foul AK, Topf MC, AlFalasi M, Chan JYK, Chaturvedi P, Chow VLY, Dietz A, Fagan JJ, Godballe C, Golusiński W, Homma A, Hosal S, Iyer NG, Kerawala C, Koh YW, Konney A, Kowalski LP, Kraus D, Kuriakose MA, Kyrodimos E, Lai SY, Leemans CR, Lennon P, Licitra L, Lou PJ, Lyons B, Mirghani H, Nichols AC, Paleri V, Panizza BJ, Parente Arias P, Patel MR, Piazza C, Rischin D, Sanabria A, Takes RP, Thomson DJ, Uppaluri R, Wang Y, Yom SS, Zhu YM, Porceddu SV, de Almeida JR, Simon C,Holsinger FC.  Recommendations for Head and Neck Surgical Oncology Practice in a Setting of Acute Severe Resource Constraint During the COVID-19 Pandemic: An International Consensus. Lancet Oncol 2020 Jun 11. doi: 10.1016/S1470-2045(20)30334-X. [ahead of print]