MOC1, MOC2 (Originally from Uppaluri lab)
Investigator NameSilvio Gutkind
Investigator InstitutionUC San Diego, Moores Cancer Center
Lab Contact NameFarhoud Faraji
Lab Contact EmailEmail hidden; Javascript is required.
Lab Contact Phone(916) 508-9300
Histology
Differentiated squamous cell carcinoma
Species
Mus musculus domesticus, C57BL/6
Site of Origin
Oral tongue
Genomic Characteristics
MOC1 - Hras mutation
MOC2 - Kras mutation
MOC22 - Hras mutation
HPV Status
Negative
Established?
Yes
Primary non-immortalized
No
Fluorescence or other transgene status
None, but available with stably transduced GFP-ffLuc (via Addgene #46793 lenti)
Engraftment sites in vivo
Orthotopic
Media Composition
IMDM/F12 (2:1) with 5% fetal calf serum, penicillin/streptomycin, 1% amphotericin, 5 ng/mL EGF (Millipore), 400 ng/mL hydrocortisone, and 5 μg/mL insulin
MTA Required
No